575003-M

α-Synuclein A53T, Human, Recombinant, E. coli

• Codice UNSPSC: 12352202
• NACRES: NA.77

Proprietà

• Saggio: ≥95% (SDS-PAGE)
• Livello qualitativo: 100
• Stato: liquid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; avoid repeated freeze/thaw cycles
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Recombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. α-synuclein is an acidic neuronal protein of 140 amino acids that has been implicated in the pathogenesis of Parkinson′s disease and related neurodegenerative disorders. α-Synuclein (A53T) is a point mutant of the α-synuclein gene that has been linked to autosomal dominant early onset Parkinson′s Disease (PD). The apparent molecular weight on SDS-PAGE is ~19-20 kDa.

Recombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. A point mutant (A53T) of α-synuclein gene that has been linked to autosomal dominant early-onset Parkinson’s disease (PD).

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

In 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.

Ricostituzione

Following initial thaw, aliquot and freeze (-20°C).

Altre note

Lashuel, H.A., et al. 2002. J. Mol. Biol.322, 1089.
Park, S.M., et al. 2002. Blood100, 2506.
Polymeropoulos, M.H., et al. 1997. Science276, 2045.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable