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345810

Millipore

G 418 Sulfate, Cell Culture Tested

G418 also known as Geneticin is an aminoglycoside antibiotic related to Gentamicin. Used as a selective agent in transfection of eukaryotic cells. Has highest potency ≥730 µg/mg and purity ≥98%.

Sinonimo/i:

G 418 Sulfate, Cell Culture Tested, G418, G 418, NMD Inhibitor I

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About This Item

Formula empirica (notazione di Hill):
C20H40N4O10 · 2H2SO4
Numero CAS:
108321-42-2
Peso molecolare:
692.71
Numero MDL:
MFCD00058314
Codice UNSPSC:
12352200

Livello qualitativo

100

Saggio

≥98% (TLC)

Forma fisica

powder

Produttore/marchio commerciale

Calbiochem®

Condizioni di stoccaggio

OK to freeze

Impurezze

≤1.0% Ammonia

Colore

white

Solubilità

water: 100 mg/mL, clear, colorless

Cationi in tracce

heavy metals: ≤100 ppm

Condizioni di spedizione

ambient

Temperatura di conservazione

10-30°C

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1
UHEPSJJJMTWUCP-NKCAIAFTSA-N

Descrizione generale

Also available as a sterile-filtered aqueous solution (Cat. No. 345812), a sterile filtered solution in 100 mM HEPES (Cat. No. 508940), and a sterile-filtered solution PBS (Cat. No. 509227).

Attenzione

Toxicity: Standard Handling (A)

Ricostituzione

Following reconstitution, sterilize by filtration through a 0.22 µm or 0.45 µm pore size filter, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Sterile stock solutions are stable for up to 1 year at -20°C.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H317,H334

Classi di pericolo

Resp. Sens. 1 - Skin Sens. 1

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Joaquín Ariño et al.
Methods in molecular biology (Clifton, N.J.), 365, 299-307 (2007-01-04)
Regulatable gene expression is a powerful genetic tool for analyzing the function of a given gene product. The use of tetracycline-regulatable promoters in yeast represents a substantial improvement over previously described methods for gene regulation. Here we show how this
Michael Nevels et al.
Methods in molecular medicine, 131, 187-195 (2007-07-28)
The last 50 yr of molecular biological investigations into human adenoviruses (Ads) have contributed enormously to our understanding of the basic principles of normal and malignant cell growth. Much of this knowledge stems from analyses of the Ad productive infection
Johannes H Hegemann et al.
Methods in molecular biology (Clifton, N.J.), 313, 129-144 (2005-08-25)
One essential step for the molecular dissection of gene function is gene inactivation. In the yeast Saccharomyces cerevisiae, elaborate tools for gene disruption are available. Gene disruption cassettes carrying completely heterologous marker genes flanked by short DNA segments homologous to
Qin Zhou et al.
Biotechnology journal, 16(9), e2000623-e2000623 (2021-05-31)
Chinese hamster ovary (CHO) cells with a high viable cell density (VCD), resilience to culture stress, and the capacity to continuously express recombinant proteins are highly desirable. Phosphatase and tension homology deleted on chromosome ten (PTEN) functions as a key
Sandra Luna et al.
Human mutation, 42(5), 551-566 (2021-02-19)
The PTEN tumor suppressor gene is mutated with high incidence in tumors and in the germline of patients with cancer predisposition or with macrocephaly associated with autism. PTEN nonsense mutations generating premature termination codons (PTC) and producing nonfunctional truncated PTEN proteins
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