341274-M

Factor H, Human

Factor H, Human, is a single-chain multi-functional glycoprotein that regulates formation and function of complement C3 and C5 convertase enzymes.

• Sinonimo/i: β _1H Globulin, β_1H Globulin
• Codice UNSPSC: 12352202
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95% (SDS-PAGE)
• Forma fisica: liquid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; avoid repeated freeze/thaw cycles
• Impurezze: IgG, IgA, IgM, Factor I, Factor B, Factor P, C3, C4, or albumin, trace (Ouchterlony)
• Temperatura di conservazione: −70°C

Descrizione

Descrizione generale

Native factor H from human serum. Single-chain glycoprotein present in normal human serum at about 500 µg/ml. Regulates formation and function of complement C3 and C5 convertase enzymes. A C3b-binding protein, not an enzyme. Regulatory activity is attributed to its ability to recognize and bind to C3b fragments.

Native factor H from human serum. Single-chain multi-functional glycoprotein present in normal human serum at about 500 µg/ml. Regulates formation and function of complement C3 and C5 convertase enzymes. A C3b-binding protein that does not exhibit enzymatic activity. Regulatory activity is attributed to its ability to recognize and bind to C3b fragments.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

In PBS, pH 7.2.

Nota sulla preparazione

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Ricostituzione

Following initial thaw, aliquot and freeze (-70°C).

Altre note

Zipfel, P.F., et al. 1999. Immunopharmacology 42, 53.
Pangburn, M.K. and Muller-Eberhard, H.J. 1984. Springer Semin. Immunopathol. 7, 163.
Fearon, D.T. and Austen, K.F. 1977. Proc. Natl. Acad. Sci. USA 74, 1683.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable