204870-M

Complement C3d, Human

Complement C3d, Human is a native, 30 kDa polypeptide formed by the limited digestion of iC3b by trypsin or elastin. The binding of C3d to CR2 on B lymphocytes enhances B cell activation.

• Sinonimo/i: Complement Protein
• Codice UNSPSC: 12352202

Proprietà

• Livello qualitativo: 100
• Saggio: ≥85% (SDS-PAGE)
• Stato: liquid
• non contiene: preservative
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; avoid repeated freeze/thaw cycles
• Impurezze: IgG, IgM, IgA, C5, Factor H, Factor I, trace
• Temperatura di conservazione: −70°C

Descrizione

Descrizione generale

Native, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30 kDa. The binding of C3d to CR2 (CD21) receptors present on B lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

In PBS, pH 7.2.

Nota sulla preparazione

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Ricostituzione

Following initial thaw, aliquot and freeze (-20°C).

Altre note

Luxembourg, A.T. and Cooper, N.R. 1994. J. Immunol.153, 4448.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA82, 4235.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable