1.00886

Ethyl 4-hydroxybenzoate sodium salt

EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF

• Sinonimo/i: Ethyl 4-hydroxybenzoate sodium salt, p-Hydroxybenzoic acid ethyl ester sodium salt, Ethylparaben sodium salt
• Formula empirica (notazione di Hill): C₉H₉NaO₃
• Numero CAS: 35285-68-8
• Peso molecolare: 188.16
• Numero MDL: MFCD00016475
• Codice UNSPSC: 12352108
• Numero indice EU: 252-487-6

Proprietà

• agenzia: BP; NF; Ph. Eur.
• Livello qualitativo: 500
• Nome Commerciale: EMPROVE^® ESSENTIAL
• Stato: solid
• pH: 10 (20 °C, 1 g/L in H₂O)
• P. ebollizione: 297 °C/1013 hPa (free ester,decomposition)
• Punto di fusione: >115 °C (free ester)
• Temp. transizione: flash point 121 °C
• Solubilità: 1000 g/L
• applicazioni: liquid formulation; ophthalmics; pharmaceutical
• Temperatura di conservazione: 15-25°C
• Stringa SMILE: [Na+].[O-]c1ccc(cc1)C(=O)OCC
• InChI: 1S/C9H10O3.Na/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6,10H,2H2,1H3;/q;+1/p-1; QYNMSPKSYXPZHG-UHFFFAOYSA-M

Descrizione

Descrizione generale

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Applicazioni

Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard ethyl 4-hydroxybenzoate.

Note legali

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H318
• Consigli di prudenza: P280 - P305 + P351 + P338
• Classi di pericolo: Eye Dam. 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 249.8 °F
• Punto d’infiammabilità (°C): 121 °C