09-796

Anti-PADI4 Antibody, CT

from rabbit

• Sinonimo/i: HL-60 PAD, PADI-H protein, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, protein-arginine deiminase, Protein-arginine deiminase type-4
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: saturated ammonium sulfate (SAS) precipitated
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: human
• tecniche: ELISA: suitable; western blot: suitable
• N° accesso NCBI: NP_036519
• N° accesso UniProt: Q9UM07
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... PADI4(23569)

Descrizione

Descrizione generale

PADI4 (Protein-arginine deiminase type-4) is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalysis of the deimination of the arginine residues. PADI4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.

Specificità

The antibody recognizes PADI4 at and around the C-terminus.

Immunogeno

Epitope: C-terminus

KLH-conjugated synthetic linear peptide corresponding to the C-terminal region of PADI4.

Applicazioni

Anti-PADI4 Antibody, C-terminus is an antibody against PADI4 for use in WB, ELISA.

ELISA: A 1:1000 dilution of a previous lot was used on ELISA.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Qualità

Evaluated by western blot on HEK293 cell lysate.

Western Blotting Analysis: 1:25-1:500 dilution of this antibody detected PADI4 in HEK293 cell lysate.

Descrizione del bersaglio

~74 kDa

Stato fisico

Format: Purified

Purified rabbit polyclonal in buffer containing PBS and 0.09% sodium azide.

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Stoccaggio e stabilità

Stable for 6 months at 2-8ºC from date of receipt. For long term storage, store at -20ºC

Risultati analitici

Control
HEK293 cell lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable