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Merck
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Key Documents

07-544

Sigma-Aldrich

Anti-phospho-nNOS/NOS I (Ser1417) Antibody

Upstate®, from rabbit

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

affinity purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

human, rat

Confezionamento

antibody small pack of 25 μg

Produttore/marchio commerciale

Upstate®

tecniche

western blot: suitable

Isotipo

IgG

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

phosphorylation (pSer1417)

Informazioni sul gene

human ... NOS1(4842)
rat ... Nos1(24598)

Descrizione generale

Note: ADMA (Catalog #19-169) and NMMA (Catalog #19-170) are inhibitors of NOS

Specificità

Predicted to cross-react with mouse, zebrafish and frog based on sequence homology.

Immunogeno

Peptide corresponding to amino acids surrounding Ser1417 of human neuronal Nitric Oxide Synthase (nNOS).

Applicazioni

Anti-phospho-nNOS/NOS I (Ser1417) Antibody is an antibody against phospho-nNOS/NOS I (Ser1417) for use in WB.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

Qualità

Tested

Descrizione del bersaglio

Mr 170kDa

Stato fisico

ImmunoAffinity Purified

Altre note

Please refer to lot specific datasheet.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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R Socodato et al.
Cell death and differentiation, 21(6), 915-928 (2014-02-18)
During early neurogenesis, retinal neuronal cells display a conserved differentiation program in vertebrates. Previous studies established that nitric oxide (NO) and cGMP accumulation regulate essential events in retinal physiology. Here we used pharmacological and genetic loss-of-function to investigate the effects
Leonardo Nogueira et al.
The Journal of physiology, 589(Pt 18), 4615-4631 (2011-07-27)
The flavanol (-)-epicatechin, a component of cacao (cocoa), has been shown to have multiple health benefits in humans. Using 1-year-old male mice, we examined the effects of 15 days of (-)-epicatechin treatment and regular exercise on: (1) exercise performance, (2)
Z P Chen et al.
American journal of physiology. Endocrinology and metabolism, 279(5), E1202-E1206 (2000-10-29)
AMP-activated protein kinase (AMPK) is a metabolic stress-sensing protein kinase responsible for coordinating metabolism and energy demand. In rodents, exercise accelerates fatty acid metabolism, enhances glucose uptake, and stimulates nitric oxide (NO) production in skeletal muscle. AMPK phosphorylates and inhibits
David J Kosek et al.
Journal of applied physiology (Bethesda, Md. : 1985), 104(5), 1476-1484 (2008-03-22)
The dystrophin-associated protein complex (DAPC) is a scaffold of proteins linking the intracellular cytoskeleton with the extracellular matrix that is integral to structural stability and integrity, signaling and mechanotransduction, and force transmission. We hypothesized that the expression of DAPC component

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