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Merck
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Key Documents

05-652

Sigma-Aldrich

Anti-MUC1/episialin Antibody, clone 214D4

clone 214D4, Upstate®, from mouse

Sinonimo/i:

Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, Episialin, H23AG, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Forma dell’anticorpo

purified antibody

Clone

214D4, monoclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Upstate®

tecniche

flow cytometry: suitable
immunohistochemistry: suitable

Isotipo

IgG1

N° accesso NCBI

NM_182741

N° accesso UniProt

P15941

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Specificità

MUC1/episialin

Immunogeno

Fusion protein, human b-gal-episialin/MUC1 repeat domain

Applicazioni

Anti-MUC1/episialin Antibody, clone 214D4 detects level of MUC1/episialin & has been published & validated for use in FC, IH.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Qualità

routinely evaluated by immunohistochemistry

Descrizione del bersaglio

none given

Stato fisico

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Chromatography

Stoccaggio e stabilità

2 years at -20°C

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Certificati d'analisi (COA)

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Neeraja Dharmaraj et al.
Biology of reproduction, 81(6), 1182-1188 (2009-08-18)
Embryo implantation involves direct interaction of the blastocyst with the luminal epithelium of the receptive uterus. MUC1, a transmembrane mucin expressed at the apical surface of uterine epithelia, acts as a barrier to microbial infection and enzymatic attack. Loss of
Ilene K Gipson et al.
Cornea, 30(12), 1346-1352 (2011-11-18)
To determine if levels of the glycocalyx membrane mucins, MUC1 and MUC16, and the secreted goblet cell mucin MUC5AC are altered in conjunctival cells and tears of postmenopausal women presenting with a history of non-Sjögren dry eye and if mucin
Kelly A Correll et al.
Biochemical and biophysical research communications, 499(4), 843-848 (2018-04-06)
TGF beta is a multifunctional cytokine that regulates alveolar epithelial cells as well as immune cells and fibroblasts. TGF beta inhibits surfactant protein A, B and C expression in fetal human lung and can inhibit type II cell proliferation induced
Pablo Argüeso et al.
The Journal of biological chemistry, 284(34), 23037-23045 (2009-06-27)
Maintenance of an intact mucosal barrier is critical to preventing damage to and infection of wet-surfaced epithelia. The mechanism of defense has been the subject of much investigation, and there is evidence now implicating O-glycosylated mucins on the epithelial cell
Timothy D Blalock et al.
Investigative ophthalmology & visual science, 49(5), 1864-1871 (2008-04-26)
Three membrane-associated mucins (MAMs)--MUC1, MUC4, and MUC16--are expressed at the ocular surface epithelium. Soluble forms of MAMs are detected in human tears, but the mechanisms of their release from the apical cells are unknown. The purpose of this study was
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