D-010

1,2-Dinitroglycerin solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₃H₆N₂O₇
• Numero CAS: 621-65-8
• Peso molecolare: 182.09
• Numero CE: 200-835-2
• Numero MDL: MFCD00661060
• Codice UNSPSC: 41116107
• ID PubChem: 329798580
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Forma fisica: liquid
• Caratteristiche: Snap-N-Spike^®/Snap-N-Shoot^®
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• Concentrazione: 1.0 mg/mL in acetonitrile
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: pharmaceutical (small molecule)
• Formato: single component solution
• Temperatura di conservazione: −20°C
• Stringa SMILE: OC[C@@H](O[N+]([O-])=O)CO[N+]([O-])=O
• InChI: 1S/C3H6N2O7/c6-1-3(12-5(9)10)2-11-4(7)8/h3,6H,1-2H2; GFVHBTOOPNJKLV-UHFFFAOYSA-N

Descrizione

Descrizione generale

1,2-Dinitroglycerin is a major plasma metabolite of the pharmaceutical vasodilator nitroglycerin. This Certified Spiking Solution^® is suitable for use in chromatography or mass spectrometry-based applications in pharmaceutical research or clinical toxicology. Nitroglycerin is used to treat heart conditions such as angina and chronic heart failure.

Applicazioni

• Pharmacokinetics of transdermal nitroglycerin: Research demonstrates the pharmacokinetic profiling of nitroglycerin and its metabolites from a transdermal delivery system, including 1,2-Dinitroglycerin, which contributes to its sustained release and absorption characteristics. This study supports its use in controlled drug delivery applications (Auclair et al., 1998).



• Nitroglycerin metabolism research: Analytical techniques for studying the metabolism of nitroglycerin, including the role of 1,2-Dinitroglycerin, were detailed, highlighting methods for examining nitrite and glutathione interactions. This research aids in understanding the metabolic pathways and implications of nitroglycerin derivatives in pharmacology (Curry et al., 1987).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H302 + H312 + H332,H319
• Consigli di prudenza: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 35.6 °F - closed cup
• Punto d’infiammabilità (°C): 2 °C - closed cup