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Key Documents

850534O

Avanti

7.9 MAG

Avanti Polar Lipids 850534O

Sinonimo/i:

1-(7Z-hexadecenoyl)-rac-glycerol

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About This Item

Formula empirica (notazione di Hill):
C19H36O4
Numero CAS:
Peso molecolare:
328.49
Codice UNSPSC:
12352211
NACRES:
NA.25

Saggio

>99% (TLC)

Forma fisica

oil

PM

328.49 g/mol

Confezionamento

pkg of 10 × 0.1 g (with screw cap (850534O-1g))
pkg of 2 × 100 mg (with screw cap (850534O-200mg))
pkg of 1 × 25 mg (with screw cap (850534O-25mg))

Produttore/marchio commerciale

Avanti Polar Lipids 850534O

tecniche

protein sequencing: suitable

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

OCC(O)COC(CCCCC/C=C\CCCCCCCC)=O

Descrizione generale

This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.

Applicazioni

7.9 MAG is suitable for use as a hosting lipid for titration to avoid lamellar crystal phase (Lc) formation during sample injection It is also suitable for use in mesocrystallization.

Azioni biochim/fisiol

7.9 MAG is a non-monoolein lipid. It can support crystallization of bacteriorhodopsin, an integral membrane protein.

Confezionamento

5 mL PTFE Vial with Screw Cap (850534O-1g)
5 mL PTFE Vial with Screw Cap (850534O-200mg)
5 mL PTFE Vial with Screw Cap (850534O-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Comunemente ordinati con questo prodotto

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids


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In Meso Crystallization of the Integral Membrane Glycerol 3-Phosphate Acyltransferase with Substrates
Li Z, et al.
Crystal Growth & Design, 18(4), 2243-2258 (2018)
Membrane protein crystallization in lipidic mesophases with tailored bilayers
Misquitta LV, et al.
Structure, 12(12), 2113-2124 (2004)
Preparation and delivery of protein microcrystals in lipidic cubic phase for serial femtosecond crystallography
Ishchenko A, et al.
Journal of Visualized Experiments, (115), e54463-e54463 (2016)
Niklaus Johner et al.
Journal of the American Chemical Society, 136(8), 3271-3284 (2014-02-06)
The recent advances in the in meso crystallization technique for the structural characterization of G-protein coupled receptor (GPCR) proteins have established the usefulness of the lipidic-cubic phases (LCPs) in the field of crystallography of membrane proteins. It is surprising that
Martin Caffrey et al.
Journal of visualized experiments : JoVE, (45) (2010-11-30)
A detailed protocol for crystallizing membrane proteins by using lipidic mesophases is described. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that

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