850530O
Avanti
7.7 MAG
Avanti Polar Lipids 850530O
Sinonimo/i:
1-(7Z-tetradecenoyl)-rac-glycerol
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About This Item
Formula empirica (notazione di Hill):
C17H32O4
Numero CAS:
Peso molecolare:
300.43
Codice UNSPSC:
12352211
NACRES:
NA.25
Prodotti consigliati
Saggio
>99% (TLC)
Forma fisica
oil
PM
300.43 g/mol
Confezionamento
pkg of 10 × 0.1 g (with screw cap (850530O-1g))
pkg of 2 × 100 mg (with screw cap (850530O-200mg))
pkg of 5 × 100 mg (with screw cap (850530O-500mg))
Produttore/marchio commerciale
Avanti Polar Lipids 850530O
tecniche
protein sequencing: suitable
Condizioni di spedizione
dry ice
Temperatura di conservazione
−20°C
Descrizione generale
Monoacylglycerols (MAGs) are glycerol esters. 7.7 MAG has a 14 carbon acyl chain and possess a bilayer thickness of 25.8 Å.
This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.
Applicazioni
7.7 MAG may be used as a host lipid in MdfA (multidrug transporter protein)–YN1074 (Fab fragment) complex for crystallization by lipidic cubic phase (LCP) method.
Azioni biochim/fisiol
Monoacylglycerols (MAGs) are used in food industry as emulsifiers. 7.7 MAG participates in meso crystallization of BtuB (vitamin B12 transporter), an outer membrane protein. It can also help in lysozyme crystal growth. 7.7 MAG also plays a key role in the growth of diffraction-quality crystals. MAGs holds high significance in pharmaceutical and food industry.
Confezionamento
5 mL PTFE Vial with Screw Cap (850530O-1g)
5 mL PTFE Vial with Screw Cap (850530O-200mg)
5 mL PTFE Vial with Screw Cap (850530O-500mg)
Note legali
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Codice della classe di stoccaggio
11 - Combustible Solids
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Kai Yu Chen et al.
Journal of agricultural and food chemistry, 67(29), 8191-8196 (2019-07-10)
Conversion of free fatty acids into monoacylglycerol gives rise to new structural properties, particularly amphipathic property. Therefore, monoacylglycerols are widely used in pharmaceutical and food industries and are also reported to facilitate better absorption into the human body. A functional
Protein
Johner N, et al.
Journal of the American Chemical Society, 136, 3271-3271 (2014)
Lisa V Misquitta et al.
Structure (London, England : 1993), 12(12), 2113-2124 (2004-12-04)
Monoacylglycerols have been used as bilayered hosts for growing crystals of membrane proteins. To date, the lipids used have had chains 16 and 18 carbon atoms long. We hypothesized that a shorter-chained lipid producing a thinner bilayer would facilitate the
Niklaus Johner et al.
Journal of the American Chemical Society, 136(8), 3271-3284 (2014-02-06)
The recent advances in the in meso crystallization technique for the structural characterization of G-protein coupled receptor (GPCR) proteins have established the usefulness of the lipidic-cubic phases (LCPs) in the field of crystallography of membrane proteins. It is surprising that
Martin Caffrey et al.
Journal of visualized experiments : JoVE, (45) (2010-11-30)
A detailed protocol for crystallizing membrane proteins by using lipidic mesophases is described. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that
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