850520P

n-dodecyl-β-D-maltoside (DDM)

Avanti Research^™ - A Croda Brand

• Sinonimo/i: DDM; lauryl maltoside; dodecyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside
• Formula empirica (notazione di Hill): C₂₄H₄₆O₁₁
• Numero CAS: 69227-93-6
• Peso molecolare: 510.62
• Codice UNSPSC: 12161902
• NACRES: NA.25

Proprietà

• Descrizione: n-dodecyl-β-D-maltopyranoside
• Saggio: >99% (contains <2% alpha isomer, TLC)
• Forma fisica: powder
• PM: 510.62 g/mol
• Confezionamento: pkg of 1 × 1 g (850520P-1g); pkg of 1 × 25 g (850520P-25g); pkg of 1 × 5 g (850520P-5g)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: OC[C@H]1O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2
• InChI: 1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1; NLEBIOOXCVAHBD-QKMCSOCLSA-N

Descrizione

Descrizione generale

n-dodecyl-β-D-maltoside (DDM) is a sugar-based surfactant.

DDM is the most widely used detergent for the isolation and purification of GPCR′s. In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form.

Applicazioni

n-dodecyl-β-D-maltoside (DDM) has been used to solubilize mitochondrial extracts of fibroblasts to perform one-dimensional blue-native PAGE (BN-PAGE) analysis for assembled oxidative phosphorylation (OXPHOS) complexes.

Azioni biochim/fisiol

n-dodecyl-β-D-maltoside (DDM) exhibits biocompatibility and biodegradability. It serves as a facilitator of electron transfer in order to decrease the oxidation potential of 3,4-ethylenedioxythiophene (EDOT). It can also increase the solubility of EDOT in aqueous solution.

Confezionamento

125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850520P-25g)

20 mL Clear Glass Screw Cap Vial (850520P-1g)

30 mL Amber Wide Mouth Screw Cap Glass Bottle (850520P-5g)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable