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850445P

Avanti

14:0-16:0 PC

1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine, powder

Sinonimo/i:

1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; MPPC; PC(14:0/16:0)

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About This Item

Formula empirica (notazione di Hill):
C38H76NO8P
Numero CAS:
69525-80-0
Peso molecolare:
705.99
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (TLC)

Stato

powder

Confezionamento

pkg of 1 × 25 mg (850445P-25mg)
pkg of 1 × 500 mg (850445P-500mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 850445P

Tipo di lipide

phospholipids
cardiolipins

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O

InChI

1S/C38H76NO8P/c1-6-8-10-12-14-16-18-19-21-23-25-27-29-31-38(41)47-36(35-46-48(42,43)45-33-32-39(3,4)5)34-44-37(40)30-28-26-24-22-20-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/t36-/m1/s1
RFVFQQWKPSOBED-PSXMRANNSA-N

Descrizione generale

Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the tissues of animal. PCs consist of saturated and unsaturated fatty acids in the sn-1 and sn-2 position respectively.

Applicazioni

14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
  • in the bilayer membrane to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC)
  • as a negative control in stimulation studies to study its effect on insect immune deficiency (IMD) pathway
  • in generating Wnt3a liposomes

Azioni biochim/fisiol

Phosphatidylcholines (PCs) participates in reducing the level of blood lipid and cholesterol.

Confezionamento

20 mL Clear Glass Screw Cap Vial (850445P-500mg)
5 mL Amber Glass Screw Cap Vial (850445P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

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Bohdana Térová et al.
Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)
In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
Li-Juan Zhao et al.
Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)
Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu
Nathan T Morrell et al.
PloS one, 3(8), e2930-e2930 (2008-08-14)
Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and
Dana K Shaw et al.
Nature communications, 8, 14401-14401 (2017-02-15)
The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that infection-derived lipids

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