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850398C

Avanti

22:1 (Cis) PC

1,2-dierucoyl-sn-glycero-3-phosphocholine, chloroform

Sinonimo/i:

1,2-di-(13Z-docosenoyl)-sn-glycero-3-phosphocholine; PC(22:1(13Z)/22:1(13Z)); DEPC

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About This Item

Formula empirica (notazione di Hill):
C52H100NO8P
Numero CAS:
51779-95-4
Peso molecolare:
898.33
Numero MDL:
MFCD00674315
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (TLC)

Stato

liquid

Confezionamento

pkg of 1 × 2.5 mL (850398C-25mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 850398C

Concentrazione

10 mg/mL (850398C-25mg)

Tipo di lipide

phospholipids
cardiolipins

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCC\C=C\CCCCCCCC)COC(=O)CCCCCCCCCCC\C=C\CCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C52H100NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,50H,6-19,24-49H2,1-5H3/b22-20+,23-21+/t50-/m1/s1
SDEURMLKLAEUAY-QVOKQPLLSA-N

Descrizione generale

22:1 (Cis) PC (1,2-dierucoyl-sn-glycero-3-phosphocholine) is a lipid derivative having a phosphocholine backbone. It has two 22 carbon fatty acid chains, each having one cis double bond at the 13th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Applicazioni

22:1 (Cis) PC (1,2-dierucoyl-sn-glycero-3-phosphocholine) has been used in liposome preparation and as a standard in the optimization of the LC−MS method conditions. It may be used to prepare planar bilayer lipid membranes (BLMs) to study its effects on the dependence of single-channel properties of C-terminal colicin peptide (P178). It may also be used in vesicles/bilayers to reconstitute the labeled protein mutant/for the reconstitution of coat protein.

Azioni biochim/fisiol

Phosphatidylcholine (PC) is capable of forming a strong bilayer.

Confezionamento

5 mL Clear Glass Sealed Ampule (850398C-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Comunemente ordinati con questo prodotto

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Classe di pericolosità dell'acqua (WGK)

WGK 3

Elenchi normativi

Forniamo informazioni su eventuali restrizioni prevalentemente per i prodotti chimici. Per altre tipologie di prodotto siamo in grado di fornire soltanto informazioni limitate. Nessuna segnalazione significa che nessuno dei componenti è citato in un elenco. È dovere dell’utilizzatore assicurarsi che il prodotto venga impiegato in maniera sicura e a norme di legge.

EU REACH Annex XVII (Restriction List)

CAS No.

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

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Chronic pain after peripheral nerve injury is associated with afferent hyperexcitability and upregulation of hyperpolarization-activated, cyclic nucleotide-regulated (HCN)-mediated IH pacemaker currents in sensory neurons. HCN channels thus constitute an attractive target for treating chronic pain. HCN channels are ubiquitously expressed;
Alexander G Karabadzhak et al.
Biophysical journal, 114(9), 2107-2115 (2018-05-10)
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The goal of this work was to develop a label-free, comprehensive, and reproducible high-resolution liquid chromatography-mass spectrometry (LC-MS)-based untargeted lipidomic workflow using a single instrument, which could be applied to biomarker discovery in both basic and clinical studies. For this
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate

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