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Merck
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Documenti fondamentali

917338

Sigma-Aldrich

PhotoHA™-RUT

methacrylated hyaluronic acid bioink kit, with ruthenium

Sinonimo/i:

3D Bioprinting, Bioink, HAMA, Hyaluronic acid

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About This Item

Codice UNSPSC:
12352201
NACRES:
NA.23

Descrizione

Methacrylated hyaluronic acid:
Degree of methacrylation: ≥ 45-65%
Product components :
Methacrylated hyaluronic acid (100 mg)
Ruthenium (100 mg)
Sodium persulfate photoinitiator (500 mg)

Livello qualitativo

100

Sterilità

sterile; sterile-filtered

PM

Mw 100-150 kDa

Temperatura di conservazione

−20°C

Applicazioni

PhotoHA™-RUT bioink kit consists of methacrylated hyaluronic acid (HAMA) and ruthenium photoinitiator. Hyaluronic acid is the most abundant glycosaminoglycan in the body being an important component of several tissues throughout the body. While it is abundant in extracellular matrices, hyaluronic acid also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions. The photoinitiator consists of ruthenium and sodium persulfate to be formulated in 1X cell culture media or PBS, which allows visible light photocrosslinking of the printed structure at 400-450 nm. PhotoHA™-RUT provides native-like 3D HA gels, and the final gel stiffness can be customized by changing HA concentrations and crosslinking.

Note legali

PhotoHA is a trademark of Advanced BioMatrix, Inc.

Avvertenze

Danger

Indicazioni di pericolo

H272,H302,H315,H317,H334,H335

Classi di pericolo

Acute Tox. 4 Oral - Ox. Sol. 3 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

5.1B - Oxidizing hazardous materials

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Michelle T Poldervaart et al.
PloS one, 12(6), e0177628-e0177628 (2017-06-07)
In bone regenerative medicine there is a need for suitable bone substitutes. Hydrogels have excellent biocompatible and biodegradable characteristics, but their visco-elastic properties limit their applicability, especially with respect to 3D bioprinting. In this study, we modified the naturally occurring

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