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Merck
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Documenti

764620

Sigma-Aldrich

Poly(D,L-lactide)

average Mn 10,000, PDI ≤1.2

Sinonimo/i:

PDLA, PLA, polyDL-lactide

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About This Item

Codice UNSPSC:
12162002
NACRES:
NA.23

Forma fisica

solid

Livello qualitativo

100

Attività ottica

[α]/D 0°, c = 0.5% in chloroform

PM

average Mn 10,000

Tempo di degradazione

<6 months

Punto di fusione

287-293 °C

Ind. polidispersione

≤1.2

Temperatura di conservazione

2-8°C

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Categorie correlate

Applicazioni

Used in Drug Delivery including coating nanoparticles1. Can be end-group functionalizated2 or used as a macroinitiator/block precursor3.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Poly(D-lactide) inherent viscosity ~1.2 dl/g

Sigma-Aldrich

67122

Poly(D-lactide)

vibrant-m

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Polylactic Acid - Biopolymer

Poly(L-lactide) mol wt 85,000-160,000

Sigma-Aldrich

P1566

Poly(L-lactide)

Resomer&#174; R 203 H, Poly(D,L-lactide) acid terminated, Mw 18,000-24,000

Sigma-Aldrich

719943

Resomer® R 203 H, Poly(D,L-lactide)

Resomer&#174; R 202 H, Poly(D,L-lactide) acid terminated, Mw 10,000-18,000

Sigma-Aldrich

719978

Resomer® R 202 H, Poly(D,L-lactide)

Poly(L-lactide) viscosity ~1.0&#160;dL/g, 0.1&#160;% (w/v) in chloroform(25&#160;°C)

Sigma-Aldrich

93578

Poly(L-lactide)

Poly(L-lactide) viscosity ~2.0&#160;dL/g, 0.1&#160;% (w/v) in chloroform(25&#160;°C)

Sigma-Aldrich

81273

Poly(L-lactide)

Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

Articoli

Electrospun Nanofibers for Drug Delivery Systems

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Fabrication of Drug-loaded Microparticles Using Hydrogel Technology and Recent Innovation in Automation

Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a given time period.

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Biodegradable Polyester-based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

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