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746983

Sigma-Aldrich

Poly(styrene)-block-poly(acrylic acid)

average Mn 38,000, 20 wt. % PAA, PDI ≤1.3

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About This Item

Formula empirica (notazione di Hill):
C4H6N(C8H8)m(C3H4O2)nH
Codice UNSPSC:
12352100
NACRES:
NA.23

Forma fisica

powder

PM

Mn 27,000-33,000 (polystyrene)
Mn 34,000-42,000 (total)
Mn 7,000-9,000 (poly(acrylic acid))
average Mn 38,000

Ind. polidispersione

≤1.3

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Applicazioni

Polystyrene-block-polyacrylic acid is a diblock copolymer used for making polymeric micelles/vesicles (polymersomes) and other encapsulation applications,. This PS-block-PAA copolymer is 20 wt. % AA; and should form micelles in water in the 30~50 nm range. The polystyrene degree of polymerization (DP) is 275 and the polyacrylic acid DP is 120.

Note legali

Sold for research purposes only and subject to field restriction: see www.sigmaaldrich.com/raftlicense.  Patents: 7,714,075; 7,250,479; 7,666,962; 6,642,318; 6,747,111; W2010/8356.

Sold for research purposes only.  Not for use in humans.  Before opening or using this product, please read the following terms and conditions.  Use of this product shall constitute acknowledgement and acceptance of these terms and conditions.
Use of this product may be covered by one or more of the following US patents and corresponding claims outside the US: 7,714,075; 7,250,479; 7,666,962; 6,642,318; 6,747,111, and pending applications (W2010/8356).  For details contact Aldrich Chemical Company, Inc.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCL2446
MKBX7436V
MKBQ5846V

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Kaoutar Moumile et al.
Journal of clinical microbiology, 42(2), 923-924 (2004-02-10)
We describe a case of primary purulent culture-negative pericarditis caused by Neisseria meningitidis serogroup C occurring in an 8-month-old previously healthy boy, which was detected in pericardial fluid by broad-spectrum PCR amplification.
Dennis E Discher et al.
Science (New York, N.Y.), 297(5583), 967-973 (2002-08-10)
Vesicles are microscopic sacs that enclose a volume with a molecularly thin membrane. The membranes are generally self-directed assemblies of amphiphilic molecules with a dual hydrophilic-hydrophobic character. Biological amphiphiles form vesicles central to cell function and are principally lipids of

Articoli

Functional RAFT Polymers for Biomedical Applications

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

Polymersomes for Drug Delivery

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

Functional Biomaterials Synthesized by Double-Head Polymerization Agents

Over the past two decades, the rapid advance of controlled living polymerization (CLP) techniques.

Functional Polymers for Biomedical Applications

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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