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710806

Sigma-Aldrich

18-Hydroxycorticosterone

97% (CP)

Sinonimo/i:

4-Pregnene-11β,18,21-triol-3,20-dione

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About This Item

Formula empirica (notazione di Hill):
C21H30O5
Numero CAS:
561-65-9
Peso molecolare:
362.46
Beilstein:
2631066
Numero CE:
209-221-9
Numero MDL:
MFCD00042685
Codice UNSPSC:
12352211
ID PubChem:
329763011
NACRES:
NA.24

Saggio

97% (CP)

Stato

powder

tecniche

mass spectrometry (MS): suitable

Temperatura di conservazione

−20°C

Stringa SMILE

O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(CO)[C@@]3([H])CC[C@]4([H])C(CO)=O)=C1

InChI

1S/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,14-17,19,22-23,25H,2-7,9-11H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1
HFSXHZZDNDGLQN-ZVIOFETBSA-N

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Confezionamento

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
To best serve customer requests, each order is packaged and shipped on demand approximately 2 weeks after receipt of an order. If you have questions regarding availability and price, please contact the Stable Isotope Customer Service Group at 937-859-1808 (1-800-448-9760 for US & Canada) or email us at isosales@sial.com.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MBBD1895
MBBC7480
MBBC5945
MBBC2988
MBBB2259V

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Paolo Mulatero et al.
The Journal of clinical endocrinology and metabolism, 97(3), 881-889 (2012-01-13)
Diagnosis of primary aldosteronism (PA) is made by screening, confirmation testing, and subtype diagnosis (computed tomography scan and adrenal vein sampling). However, some tests are costly and unavailable in most hospitals. The aim of the study was to evaluate the
P Vecsei et al.
Journal of steroid biochemistry, 19(1A), 345-351 (1983-07-01)
The value of the urine tests: free aldosterone, aldosterone-18-glucuronide, tetrahydroaldosterone 18-hydroxycorticosterone and 18-hydroxydeoxycorticosterone in distinguishing primary aldosteronism from essential hypertension was studied in patients with typical and atypical primary aldosteronism and in patients with essential hypertension. The discriminating function of
N Sonino et al.
Clinical endocrinology, 14(1), 31-39 (1981-01-01)
The effect of 24-h metyrapone administration on adrenal mineralocorticoid and glucocorticoid pathways has been studied in normal children. Urine and serum steroid concentrations were evaluated. Simultaneous determinations of deoxycorticosterone (DOC), corticosterone (B), cortisol (F), and aldosterone (aldo), in both urine
Richard J Auchus et al.
The Journal of clinical endocrinology and metabolism, 92(7), 2648-2651 (2007-05-03)
In primary aldosteronism, elevated serum 18-hydroxycorticosterone (18OHB) suggests aldosterone-producing adenoma (APA) rather than bilateral, idiopathic hyperaldosteronism (IHA), but little is known about the relative production of 18OHB and aldosterone (A) in APAs compared with IHA. We measured 18OHB, A, and
M Peter et al.
The Journal of clinical endocrinology and metabolism, 80(5), 1622-1627 (1995-05-01)
Aldosterone (Aldo), the most potent mineralocorticoid, is synthesized in the adrenal zona glomerulosa, requiring 11 beta-hydroxylation of 11-deoxycorticosterone (DOC) to form corticosterone (B), hydroxylation at position C18 to form 18-hydroxycorticosterone (18-OHB), and finally oxidation at position C18. There is a
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