536822

PAMAM-OH dendrimer, generation 6 solution

5 wt. % in methanol

• Formula condensata: [NH₂(CH₂)₂NH₂]:(G=6);dendri PAMAM(NHCH₂CH₂OH)₂₅₆
• Peso molecolare: 58298.21
• Numero MDL: MFCD00197936
• Codice UNSPSC: 12162002
• NACRES: NA.25

Proprietà

• Descrizione: amidoethanol surface groups
• Livello qualitativo: 100
• Forma fisica: liquid
• PM: generation 6
• Caratteristiche: core type ethylenediamine core (2-carbon core)
• Concentrazione: 5 wt. % in methanol
• N° gruppi superficiali: 256
• Indice di rifrazione: n20/D 1.336
• Densità: 0.807 g/mL at 25 °C
• Temperatura di conservazione: 2-8°C

Descrizione

Descrizione generale

PAMAM-OH (poly(amidoamine) dendrimers are highly branched core-shell nanostructures with surface hydroxyl groups. The presence of hydroxyl groups on the surface of the PAMAM-OH dendrimer molecule leads to stronger interaction with the components of the cell membrane via the formation of hydrogen bonds. This type of interaction can modify the properties and function of cell membranes. PAMAM-OH dendrimers also have an advantage over PAMAM dendrimers in terms of cytotoxicity and aggregation problems because of the absence of amine functionality.

Applicazioni

PAMAM-OH dendrimer can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers.

Stato fisico

Contains 256 surface hydroxyl groups.

Note legali

Manufactured by Dendritech^®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H301 + H311 + H331,H370
• Consigli di prudenza: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organi bersaglio: Eyes
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 51.8 °F - closed cup
• Punto d’infiammabilità (°C): 11 °C - closed cup