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Merck
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Documenti fondamentali

357898

Sigma-Aldrich

Serinol

98%

Sinonimo/i:

2-Amino-1,3-propanediol

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About This Item

Formula condensata:
HOCH2CH(NH2)CH2OH
Numero CAS:
Peso molecolare:
91.11
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

98%

P. eboll.

277 °C (lit.)

Punto di fusione

52-55 °C (lit.)

Gruppo funzionale

amine
hydroxyl

Stringa SMILE

NC(CO)CO

InChI

1S/C3H9NO2/c4-3(1-5)2-6/h3,5-6H,1-2,4H2
KJJPLEZQSCZCKE-UHFFFAOYSA-N

Descrizione generale

Serinol activates toxin production in the attenuated cultures of Helminthosporium sacchari. Preparation of polyesters derived from serinol is reported.

Applicazioni

Serinol may be used to prepare the artificial nucleic acids. It may be used in the synthesis of N-acylated serinol and C16-serinol affinity gel.

Pittogrammi

Corrosion

Avvertenze

Danger

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Eye Dam. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

235.4 °F - closed cup

Punto d’infiammabilità (°C)

113 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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E Bieberich et al.
The Journal of biological chemistry, 275(1), 177-181 (2000-01-05)
A novel structural analog of ceramide was synthesized by N-acylation of serinol (2-amino-1,3-propanediol) and studied for its effects on glycolipid biosynthesis and cell differentiation of neuroblastoma cells. Incubation with N-palmitoylated serinol (C16-serinol) increased the concentration of endogenous ceramide by 50-80%
F Pinkerton et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(11), 4007-4011 (1976-11-01)
Successive transfer in synthetic medium of spores and mycelial fragments from original toxin-producing cultures of Helminthosporium sacchari results in attenuated cultures which do not produce the host-specific toxin helminthosporoside. When attenuated cultures are grown on material obtained from the water
Hiroyuki Asanuma et al.
Chemical record (New York, N.Y.), 14(6), 1055-1069 (2014-08-30)
In this account, we demonstrate a new methodology for the de novo design of functional oligonucleotides with the acyclic scaffolds threoninol and serinol. Four functional motifs-wedge, interstrand-wedge, dimer, and cluster-have been prepared from natural DNA or RNA and functional base
Daniele Locatelli et al.
Nanomaterials (Basel, Switzerland), 10(6) (2020-06-21)
The solubility parameters of multiwalled carbon nanotubes (CNTs) was tuned via their chemical modification with pyrrole compounds (PyCs), by means of a simple and sustainable methodology. PyCs were synthesized with high atom efficiency through the Paal-Knorr reaction of primary amines
B N Trawick et al.
Bioconjugate chemistry, 12(6), 900-905 (2001-11-22)
The syntheses and RNA cleavage efficiencies of a new series of oligonucleotide conjugates of Cu(II)-serinol-terpyridine and 1,3-propanediol are reported. These reagents, termed ribozyme mimics, were designed such that they would yield multiple unpaired RNA residues directly opposite the site of

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