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Merck

PRKCH

protein kinase C, eta

Sinonimi:
PKC-L, PKCL, PRKCL, nPKC-eta
Specie:
ID UniProtKB:
ID gene:
  • Human(5583) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq, Jul 2008]
  • Mouse(18755) protein kinase C, eta
  • Rat(81749) protein kinase C, eta
  • cow(518542) protein kinase C, eta
  • sheep(101105574) protein kinase C, eta
  • naked mole-rat(101716769) protein kinase C, eta
  • Domestic Rabbit(100344184) protein kinase C, eta
  • domestic guinea pig(100736222) protein kinase C, eta
  • chicken(423518) protein kinase C, eta
  • Horse(100051560) protein kinase C, eta
  • domestic cat(101082413) protein kinase C, eta
  • dog(490722) protein kinase C, eta

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Acido oleico, ≥99% (GC),
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-phospho-PKCη (Thr655) Antibody, Upstate®, from rabbit,
Reattività con
human
Applicazione
western blot
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-PRKCH antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Xanthone, 97%,
Specie
mouse
H-7 dihydrochloride, ≥98% (HPLC),
Specie
human
Tamoxifen citrate salt, ≥99%,
Specie
human
Acido oleico, ≥99% (GC),
Specie
human
UCN-01, ≥97% (HPLC), powder,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
PKC η Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKC eta. For use in Kinase Assays.,
Specie
human
PKCη, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Prkch,
Specie
mouse
MISSION® esiRNA, targeting human PRKCH,
Specie
human