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Merck

PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit

Sinonimi:
AMPKG
Specie:
ID UniProtKB:
ID gene:
  • Human(5571) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(19082) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Rat(25520) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Zebrafish(406440) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • chicken(429688) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • dog(486559) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Horse(100034096) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • domestic cat(101094684) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • naked mole-rat(101721085) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Domestic Rabbit(100356542) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • domestic guinea pig(100716757) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • cow(282324) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • sheep(101103143) protein kinase, AMP-activated, gamma 1 non-catalytic subunit

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PRKAG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-PRKAG1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-PRKAG1 (center) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
ELISA
immunohistochemistry

western blot
Anti-PRKAG1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot

Proteins

N° Catalogo
Descrizione
Specie
AMPK (α1/β1/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
AMPK (α2/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
AMPK (α1/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human PRKAG1,
Specie
human
MISSION® esiRNA, targeting mouse Prkag1,
Specie
mouse