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Merck

PPP1CA

protein phosphatase 1, catalytic subunit, alpha isozyme

Sinonimi:
PP-1A, PP1A, PP1alpha, PPP1A
Specie:
ID UniProtKB:
ID gene:
  • Human(5499) Summary: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19045) protein phosphatase 1, catalytic subunit, alpha isoform
  • Rat(24668) protein phosphatase 1, catalytic subunit, alpha isozyme
  • dog(403609) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Horse(100059233) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic cat(101080405) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic guinea pig(100721697) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Domestic Rabbit(100009298) protein phosphatase 1, catalytic subunit, alpha isozyme
  • naked mole-rat(101705408) protein phosphatase 1, catalytic subunit, alpha isozyme
  • cow(516175) protein phosphatase 1, catalytic subunit, alpha isozyme
  • sheep(101119264) protein phosphatase 1, catalytic subunit, alpha isozyme

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PP1-α antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-PPP1CA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-Phospho-PPP1CA-T320 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Rabbit anti-PPP1CA Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
Anti-ZAP-70 Antibody, clone 1E7.2, clone 1E7.2, Upstate®, from mouse,
Reattività con
human, mouse
Applicazione
immunocytochemistry
immunoprecipitation (IP)

western blot

Proteins

N° Catalogo
Descrizione
Specie
PP1α Protein, 10 µg, Recombinant, full length, human PP1α, for use in Phosphatase Assays.,
Specie
human
Protein Phosphatase-1 Catalytic Subunit, α-Isoform from rabbit, 5,000-15,000 units/mg protein, recombinant, expressed in E. coli, lyophilized powder,
Specie
domestic rabbit
PP1A, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human PPP1CA,
Specie
human
MISSION® esiRNA, targeting mouse Ppp1ca,
Specie
mouse