NPHS1
nephrosis 1, congenital, Finnish type (nephrin)
Sinonimi:
CNF, NPHN, nephrin
Specie:
Human NPHS1 (4868), Mouse Nphs1 (54631), Rat Nphs1 (64563), sheep NPHS1 (101115895), naked mole-rat Nphs1 (101705086), Domestic Rabbit NPHS1 (100354996), domestic guinea pig Nphs1 (100713185), Zebrafish nphs1 (692352), domestic cat NPHS1 (101101018), dog NPHS1 (484571)
ID UniProtKB:
ID gene:
- Human(4868) Summary: This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
- Mouse(54631) nephrosis 1, nephrin
- Rat(64563) nephrosis 1, congenital, Finnish type (nephrin)
- sheep(101115895) nephrosis 1, congenital, Finnish type (nephrin)
- naked mole-rat(101705086) nephrosis 1, congenital, Finnish type (nephrin)
- Domestic Rabbit(100354996) nephrosis 1, congenital, Finnish type (nephrin)
- domestic guinea pig(100713185) nephrosis 1, congenital, Finnish type (nephrin)
- Zebrafish(692352) nephrosis 1, congenital, Finnish type (nephrin)
- domestic cat(101101018) nephrosis 1, congenital, Finnish type (nephrin)
- dog(484571) nephrosis 1, congenital, Finnish type (nephrin)
- cow(519706) nephrosis 1, congenital, Finnish type (nephrin)
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Nephrin antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Nephrin Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
MONOCLONAL ANTI-NEPHRIN antibody produced in mouse, clone 174CT2.1.1, crude ascites, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot
western blot
Monoclonal Anti-NPHS1 antibody produced in mouse, clone 3H6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Anti-Nephrin Antibody, clone 3B6.1, clone 3B6.1, from mouse,
Reattività con
human
Applicazione
western blot