Passa al contenuto
Merck

KCNN1

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

Sinonimi:
KCa2.1, SK1, SKCA1, hSK1
Specie:
ID UniProtKB:
ID gene:
  • Human(3780) Summary: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008]
  • Mouse(84036) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • Rat(54261) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • domestic guinea pig(100715012) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • naked mole-rat(101717556) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • sheep(101112056) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • dog(484829) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • cow(408008) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • domestic cat(101085608) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Apamin, from bee venom, ≥95% (HPLC),
Specie
rat
Apamin, synthetic, ≥97% (HPLC),
Specie
rat

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-KCNN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-KCNN1 antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
human
Applicazione
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human KCNN1,
Specie
human