AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
Sinonimi:
AIF, CMTX4, COWCK, COXPD6, PDCD8
Specie:
Human AIFM1 (9131), Mouse Aifm1 (26926), Rat Aifm1 (83533), Zebrafish aifm1 (373125), cow AIFM1 (535714), Horse AIFM1 (100054546), domestic cat AIFM1 (768258), dog AIFM1 (481048), chicken AIFM1 (428688), naked mole-rat Aifm1 (101698690) ...Più
ID UniProtKB:
ID gene:
- Human(9131) Summary: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010]
- Mouse(26926) apoptosis-inducing factor, mitochondrion-associated 1
- Rat(83533) apoptosis-inducing factor, mitochondrion-associated 1
- Zebrafish(373125) apoptosis-inducing factor, mitochondrion-associated 1
- cow(535714) apoptosis-inducing factor, mitochondrion-associated, 1
- Horse(100054546) apoptosis-inducing factor, mitochondrion-associated, 1
- domestic cat(768258) apoptosis-inducing factor, mitochondrion-associated, 1
- dog(481048) apoptosis-inducing factor, mitochondrion-associated, 1
- chicken(428688) apoptosis-inducing factor, mitochondrion-associated, 1
- naked mole-rat(101698690) apoptosis-inducing factor, mitochondrion-associated, 1
- domestic guinea pig(100730787) apoptosis-inducing factor, mitochondrion-associated, 1
- sheep(101121574) apoptosis-inducing factor, mitochondrion-associated, 1
- sheep(100188912) apoptosis-inducing factor, mitochondrion-associated, 1
- Domestic Rabbit(100347778) apoptosis-inducing factor, mitochondrion-associated, 1
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-AIF Antibody, clone 1E4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, feline, human, monkey, mouse, porcine, rat
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-AIF (Apoptosis Inducing Factor) Antibody, Upstate®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
western blot
Anticorpo anti-AIF, dominio interno, Chemicon®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Anti-AIF antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot