UC177

(±)-Mephenytoin

• Synonym(s): (±)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione, (±)-5-Ethyl-3-methyl-5-phenylhydantoin
• Empirical Formula (Hill Notation): C₁₂H₁₄N₂O₂
• CAS Number: 50-12-4
• Molecular Weight: 218.25
• EC Number: 200-012-8
• MDL number: MFCD00022407
• UNSPSC Code: 12161501
• PubChem Substance ID: 329827653

Properties

• form: crystals
• Quality Level: 200
• color: off-white
• mp: 115-118 °C; 135-137 °C
• solubility: DMSO: soluble
• storage temp.: 2-8°C
• SMILES string: CCC1(NC(=O)N(C)C1=O)c2ccccc2
• InChI: 1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)
• InChI key: GMHKMTDVRCWUDX-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Description

Biochem/physiol Actions

CYP2B6 and CYP2C19 substrate; anticonvulsive, antiepileptic.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

(±)-Mephenytoin is soluble in DMSO.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves