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Key Documents

SML3832

Sigma-Aldrich

Alnustone

≥98% (HPLC)

Synonym(s):

(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one

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About This Item

Empirical Formula (Hill Notation):
C19H18O
CAS Number:
Molecular Weight:
262.35
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

Alnustone is a diarylheptanoid isolated from Alpinia katsumadai Hayata, rhizomes of Curcuma xanthorrhiza and other plants that exhibits anti-hyperglycemic, anti-inflammatory, antihepatotoxic and antiemetic activities. Alnustone is a potent inhibitor of the Thyroid Adenoma Associated (THADA) function, which reverses THADA-induced β-cell dysfunction and ameliorate hyperglycemia in obese mice. It significantly decreases fed blood glucose and improved glucose tolerance in mice.

Caution

Hygroscopic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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