SAB5801054
Goat Anti-Chicken IgY HRP Alpaca Heavy chain only Antibody
recombinant Alpaca(VHH) Nano antibody
Synonym(s):
Recombinant Alpaca single variable domain secondary Nanobody
About This Item
Recommended Products
biological source
alpaca
recombinant
expressed in HEK 293 cells (Human cell line)
conjugate
horse radish peroxidase (HRP)
antibody form
affinity purified immunoglobulin
antibody product type
secondary antibodies
clone
recombinant monoclonal
form
lyophilized solid
mol wt
100 kDa
species reactivity
chicken, Alpaca
technique(s)
ELISA: 1:10000-1:50000
western blot: 1:10000-1:50000
General description
Hens egg yolk immunoglobulins IgY can be transferred from the serum of mother hen to the offspring egg yolk to acquire immunity. In the immunodiagnostic technologies, IgY is an excellent antibody for using in immunological assays involving mammalian sera, due to discriminative properties of IgY compared to mammalian IgG, as IgY does not react with the rheumatoid factor and human anti-mouse IgG antibodies do not activate the complement system and do not bind to Fc receptor. Also, they have poor cross reactivity to mammalian IgG due to immunological differences. IgY does not contain a hinge region but does contain an additional constant domain. The whole IgY molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgYcontains two heavy and light chains. The common IgY is monomeric with a molecular weight of approximately 170 kDa.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.
Specificity
Isotype: VHH domain of alpaca IgG2b/2c fused to goat IgG Fc
Immunogen
Packaging
Physical form
Reconstitution
Storage and Stability
Other Notes
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3 - Skin Sens. 1
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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