SAB4501746

Anti-Galectin 3 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): 35 kDa lectin, CBP 35, Carbohydrate binding protein 35, GALBP, Galactose-specific lectin 3
• MDL number: MFCD01633374
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 26 kDa
• species reactivity: rat, human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P17931
• UniProt accession no.: P17931
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... LGALS3(3958)

Description

General description

Anti-Galectin 3 Antibody detects endogenous levels of total Galectin 3 protein.
Galectin 3 is a carbohydrate-binding protein. It is abundantly expressed in the extracellular matrix, the cytoplasm and the nucleus. It contains an intrinsically disordered N-terminal domain and a canonical CRD (carbohydrate recognition domain). It is mapped to human chromosome 14q22.

Immunogen

The antiserum was produced against synthesized peptide derived from human Galectin 3.

Immunogen Range: 141-190

Biochem/physiol Actions

Galectin 3 controls cell activation, migration, adhesion and signaling. It plays a role in cancer progression after it is initiated. Expression of galectin-3 regulates apoptosis and development of T-cell. It participates in several physiological and pathological processes like pre-mRNA splicing, neoplastic transformation and immune responses.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable