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Key Documents

S1006

Sigma-Aldrich

Sulfatides from bovine brain

Synonym(s):

Cerebroside sulfate

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About This Item

UNSPSC Code:
12352200

Quality Level

storage temp.

−20°C

General description

Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. It is localized in myelin sheath and comprises approximately 4% of total myelin lipid in brain.

Application

Sulfatides has been used in:
  • enzyme linked immunosorbent assay (ELISA) in human plasma samples
  • thin layer chromatography in myelin membranes
  • in sulfatide binding assay of properdin

Biochem/physiol Actions

Sulfatides play a key role in physiological processes of nervous system, immune system and in insulin secretion. Anomalies in sulfatides catabolism in lysosome is implicated in late infantile metachromatic leukodystrophy. High levels of sulfatides is also observed in ovarian cancer. Sulfatides contribute to the pathogenesis of chronic inflammatory diseases of the central nervous system.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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