N9876
4-Nitrophenyl butyrate
lipase substrate, chromogenic, esterase substrate, ≥98%, liquid
Synonym(s):
p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
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About This Item
Empirical Formula (Hill Notation):
C10H11NO4
CAS Number:
Molecular Weight:
209.20
Beilstein:
1879729
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83
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Product Name
4-Nitrophenyl butyrate, ≥98%
Quality Level
Assay
≥98%
form
liquid
density
1.19 g/mL at 20 °C (lit.)
storage temp.
−20°C
SMILES string
CCCC(=O)Oc1ccc(cc1)[N+]([O-])=O
InChI
1S/C10H11NO4/c1-2-3-10(12)15-9-6-4-8(5-7-9)11(13)14/h4-7H,2-3H2,1H3
InChI key
DVDUMIQZEUTAGK-UHFFFAOYSA-N
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General description
4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.
Application
4-nitrophenyl butyrate has been used:
- as a substrate for esterase activity in monocyte-derived macrophage cell line in response to polyethylene
- as a substrate for mycobacterial phospholipase A and mycobacterial cutinase activity
- as a substrate to determine the effect of buffers and solvents on human carboxylesterase
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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