D3439
D-erythro-Dihydrosphingosine 1-phosphate
≥98% (TLC), waxy solid
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About This Item
Empirical Formula (Hill Notation):
C18H40NO5P
CAS Number:
Molecular Weight:
381.49
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥98% (TLC)
form
waxy solid
color
yellow
solubility
methanol: THF: water (6:3:1): >0.5 mg/mL
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)COP(O)(O)=O
InChI
1S/C18H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1
InChI key
YHEDRJPUIRMZMP-ZWKOTPCHSA-N
Gene Information
human ... S1PR1(1901) , S1PR2(9294) , S1PR3(1903) , S1PR4(8698) , S1PR5(53637)
Biochem/physiol Actions
Negative control for sphingosine-1-phosphate.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Van Brocklyn, J.R., et al.
The Journal of Biological Chemistry, 142, 229-229 (1998)
Sang Won Park et al.
Laboratory investigation; a journal of technical methods and pathology, 90(8), 1209-1224 (2010-05-12)
Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine-1-phosphate (S1P) levels. Furthermore, exogenous sphinganine-1-phosphate protected against both liver
Mia Roest Laursen et al.
Metabolomics : Official journal of the Metabolomic Society, 13(6), 67-67 (2017-05-06)
Remote ischemic conditioning (RIC) is a maneuver by which short non-lethal ischemic events are applied on distant organs or limbs to reduce ischemia and reperfusion injuries caused by e.g. myocardial infarct. Although intensively investigated, the specific mechanism of this protective
Ryunosuke Ohkawa et al.
Clinical biochemistry, 48(10-11), 690-697 (2015-04-12)
Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid mediator. Although the plasma S1P concentration is reportedly determined by cellular components, including erythrocytes, platelets, and vascular endothelial cells, the possible involvement of other factors, such as serum sphingomyelin (SM) and autotaxin (ATX)
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