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D-(+)-Cellobiose

≥99.0%, suitable for microbiology, Reducing sugar disaccharide

Synonym(s):

Cellobiose, Cellose, Beta-Cellobiose, D-Cellobiose, β-D-Glc-(1→4)-D-Glc, 4-O-β-D-Glucopyranosyl-D-glucose

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About This Item

Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein:
93795
EC Number:
MDL number:
UNSPSC Code:
41106212
PubChem Substance ID:
NACRES:
NA.85

Quality Level

Assay

≥99.0% (HPLC)
≥99.0%

form

powder

optical activity

[α]20/D +34±1°, 15 hr, c = 10% in H2O

mol wt

342.30 g/mol

ign. residue

≤0.1% (as SO4)

loss

≤1% loss on drying, 110 °C

mp

~235 °C (dec.)
239 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

As: ≤0.1 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤150 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

microbiology

SMILES string

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O

InChI

1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12-/m0/s1

InChI key

DKXNBNKWCZZMJT-WELRSGGNSA-N

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General description

Cellobiose is a disaccharide that is a reducing sugar. It is added to culture media as a nutrient supplement, specifically as a carbohydrate source, and can be used to differentiate bacteria based on their ability to ferment cellobiose. For example, Vibrio spp. can ferment cellobiose which results in acid production and can be indicated by the pH indicator bromothymol blue, which turns yellow at acidic pH. The addition of cellobiose in the media also stimulates the initial growth of Salmonella.

Application

Cellobiose has applications as a carbohydrate source in culture media and biochemical characterization of microorganisms, based on their carbohydrate fermentation abilities

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Corinna Schiano-di-Cola et al.
The FEBS journal, 287(12), 2577-2596 (2019-11-23)
Thermostable cellulases from glycoside hydrolase family 7 (GH7) are the main components of enzymatic mixtures for industrial saccharification of lignocellulose. Activity improvement of these enzymes via rational design is a promising strategy to alleviate the industrial costs, but it requires
Lara Hassan et al.
mBio, 10(4) (2019-07-04)
It is essential for microbes to acquire information about their environment. Fungi use soluble degradation products of plant cell wall components to understand the substrate composition they grow on. Individual perception pathways have been well described. However, the interconnections between
Hoi Yee Keung et al.
Applied and environmental microbiology, 83(7) (2017-01-25)
Bifidobacteria exert beneficial effects on hosts and are extensively used as probiotics. However, due to the genetic inaccessibility of these bacteria, little is known about their mechanisms of carbohydrate utilization and regulation. Bifidobacterium breve strain JCM1192 can grow on water-insoluble
Teck Wei Ching et al.
Carbohydrate polymers, 157, 1794-1800 (2016-12-19)
One of the grand challenges of this century is to transition fuels and chemicals production derived from fossil feedstocks to renewable feedstocks such as cellulosic biomass. Here we describe fast microwave conversion of microcrystalline cellulose (MCC) in water, with dilute
Agustina Llanos et al.
Microbial cell factories, 18(1), 14-14 (2019-01-30)
Research on filamentous fungi emphasized the remarkable redundancy in genes encoding hydrolytic enzymes, the similarities but also the large differences in their expression, especially through the role of the XlnR/XYR1 transcriptional activator. The purpose of this study was to evaluate

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