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MAB4337

Sigma-Aldrich

Anti-UTF-1 Antibody, clone 5G10.2

clone 5G10.2, Chemicon®, from mouse

Synonym(s):

Anti-AI505934

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

5G10.2, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

input

sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)
sample type: human embryonic stem cell(s)

isotype

IgG1κ

NCBI accession no.

NM_003577.2

UniProt accession no.

Q5T230

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... UTF1(8433)

General description

UTF1 is a transcription factor that was originally identified due to its expression in Embryonic Stem (ES) cells, Embryonic Carcinoma (EC) cells, and germ line tissues. Expression was not found in adult tissues. It was thought at the time that UTF1 might play an important role in early molecular events of embryogenesis. Subsequent studies have shown that UTF1 is a target of the Oct-4 / Sox-2 complex, a key determinant of pluripotency in stem cells

Immunogen

Recombinant GST Fusion protein, human UTF-1

Application

Anti-UTF-1 Antibody, clone 5G10.2 detects level of UTF-1 & has been published & validated for use in ELISA, WB & IC.

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xiao-Ling Wu et al.
Carcinogenesis, 34(7), 1660-1668 (2013-03-29)
Undifferentiated embryonic cell transcription factor-1 (UTF1) is an important transcription factor during development, which plays critical roles in cell fate determination. However, its expression and function in somatic tissues remain unclear. Here, we investigated the expression pattern of the UTF1
M Nishimoto et al.
Molecular and cellular biology, 19(8), 5453-5465 (1999-07-20)
UTF1 is a transcriptional coactivator which has recently been isolated and found to be expressed mainly in pluripotent embryonic stem (ES) cells (A. Okuda, A. Fukushima, M. Nishimoto, et al., EMBO J. 17:2019-2032, 1998). To gain insight into the regulatory
Functional characterization of single-nucleotide polymorphisms in the human undifferentiated embryonic-cell transcription factor 1 gene.
Rajkumar P Thummer,Loes J Drenth-Diephuis,Karen E Carney,Bart J L Eggen
Dna and Cell Biology null
Characterization of human UTF1, a chromatin-associated protein with repressor activity expressed in pluripotent cells.
Susanne M Kooistra,Rajkumar P Thummer,Bart J L Eggen
Stem Cell Research null
Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms.
Kristensen, DM; Nielsen, JE; Skakkebaek, NE; Graem, N; Jacobsen, GK; Rajpert-De Meyts, E; Leffers, H
Human Reproduction null
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