Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

MAB2120Z

Sigma-Aldrich

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free

clone ERIC-1, Chemicon®, from mouse

Synonym(s):

NeuralCellAdhesionMolecule, CD56, MAB2120

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

ERIC-1, monoclonal

species reactivity

human, pig

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

suitability

not suitable for flow cytometry

NCBI accession no.

NM_000615.5
NM_001076682.2
NM_181351.3

UniProt accession no.

P13591

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NCAM1(4684)

General description

The previously assigned protein identifier P13592 has been merged into P13591. Full details can be found on the UniProt database.

Specificity

Recognizes N-CAM expressed on developing and adult neuroectrodermal tissues in Humans. Neuroectodermal tumors also stain including Elioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumor are also highly reactive. Will react on Natural Killer cells. Recognizes 120, 140 and 180 kDa NCAM isoforms.

Immunogen

Epitope: extracellular
Human Retinoblastoma tumor

Application

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free is an antibody against NCAM for use in ELISA, WB, IH.
Immunohistology on frozen tissue sections acetone fixation only.

Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms.

ELISA: 80 ng/mL

Does not work in flow cytometry.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Growth Cones & Axon Guidance

Neurofilament & Neuron Metabolism

Linkage

Replaces: MAB2122

Physical form

Format: Purified
Liquid in PBS. Does not contain any preservatives

Storage and Stability

Store at -20°C only. Avoid repeated freeze-thaw cycles.

Analysis Note

Control
Recommended positive control tissue: Neuroblastoma

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells.
Hauck, SM; Kinkl, N; Deeg, CA; Swiatek-de Lange, M; Schoffmann, S; Ueffing, M
Molecular and cellular biology null
Priyadarsini Kumar et al.
PloS one, 10(8), e0135089-e0135089 (2015-08-13)
Trophoblast differentiation during early placental development is critical for successful pregnancy and aberrant differentiation causes preeclampsia and early pregnancy loss. During the first trimester, cytotrophoblasts are exposed to low oxygen tension (equivalent to~2%-3% O2) and differentiation proceeds along an extravillous

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service