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Key Documents

CBL481

Millipore

Anti-Integrin β1 Antibody, clone TDM29

clone TDM29, Chemicon®, from mouse

Synonym(s):

CD29, platelet GPIIa, VLA beta1-chain, fibronectin receptor beta chain

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

TDM29, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGB1(3688)

Specificity

The antibody reacts with the integrin beta1 chain which is a membrane glycoprotein (130 kDa) that can complex with the 6 different alpha-chains of the VLA′s. It is also known as VLA beta1-chain and the fibronectin receptor. The antigen is not expressed on erythrocytes and only weakly stains granulocytes.

Antigen distribution:
T cells: 40 ± 10%
CD4+ cells: 40 ± 20%
CD8+ cells: 40 ± 15%
B cells: 20 ± 5%

Immunogen

U937 cells

Application

Anti-Integrin β1 Antibody, clone TDM29 is an antibody against Integrin β1 for use in FC, IF & IP.
Research Category
Cell Structure
Research Sub Category
Integrins

Physical form

Format: Purified
Immunoglobulin purified by Protein A affinity chromatography and presented in PBS containing 1mg/mL BSA and 10mM sodium azide

Storage and Stability

Maintain at 2°-8°C for up to 12 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms.
Faheem M Shaikh,Eric C Seales,William C Clem,Kristin M Hennessy,Ya Zhuo,Susan L Bellis
Experimental Cell Research null
Prominent collagen type VI expression in juvenile angiofibromas.
Monika Gramann,Olaf Wendler,Lothar Haeberle,Bernhard Schick
Histochemistry and Cell Biology null
Triantafyllos Chavakis et al.
Blood, 105(3), 1036-1043 (2004-09-24)
Angiogenesis and inflammation are closely related biologic processes in wound healing and the responses to vascular injury as well as in cardiovascular diseases; however, the molecular connections are poorly defined. In particular, it is yet unclear whether endogenous factors can
Melissa M Ledet et al.
Scientific reports, 10(1), 20580-20580 (2020-11-27)
Determining mechanisms that naturally protect species from developing cancer is critical in order to prevent and treat cancer. Here, we describe a novel cancer-suppressing mechanism, via the secretion of bioactive factors by mammary cells, that is present in domesticated mammals
Ralf Kaiser et al.
Journal of cellular and molecular medicine, 16(10), 2387-2393 (2012-02-23)
Homing of endothelial progenitor cells (EPCs) is crucial for neoangiogenesis, which might be negatively affected by hypoxia. We investigated the influence of hypoxia on fibronectin binding integrins for migration and cell-matrix-adhesion. AMP-activated kinase (AMPK) and integrin-linked kinase (ILK) were examined

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