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V-030

Supelco

Vitamin K1 solution

10 μg/mL in ethanol, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C31H46O2
CAS Number:
84-80-0
Molecular Weight:
450.70
MDL number:
MFCD00214063
UNSPSC Code:
12352205
PubChem Substance ID:
329828971
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

10 μg/mL in ethanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

-143.99 °C

application(s)

clinical testing
clinical testing

format

single component solution

shipped in

wet ice

storage temp.

−70°C

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1

InChI key

MBWXNTAXLNYFJB-NKFFZRIASA-N

General description

Vitamin K1 (phylloquinone) is a fat-soluble vitamin that serves as a cofactor for vitamin K-dependent (VKD) proteins and enzymes which activate blood-clotting factors. Vitamin K1 is critical to many physiological processes including bone metabolism, arterial calcification, growth control, and signal transduction.

Application

This certified solution standard is suitable for use as starting material in the preparation of linearity standards, calibrators, or controls in LC-MS/MS vitamin K1 clinical testing applications such as assessment of vitamin K deficiency as well as food and nutrition testing applications by HPLC.
Vitamin K1 (phylloquinone) may be used as a certified reference material (CRM) for the determination of the analyte in biological and food samples by high-performance liquid chromatography (HPLC) method.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

57.2 °F - closed cup

Flash Point(C)

14.0 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of phylloquinone in oils, margarines and butter by high-performance liquid chromatography with electrochemical detection
Piironen V, et al.
Food Chemistry, 59(3), 473-480 (1997)
Determination of phylloquinone and menaquinones in food
Schurgers LJ and Vermeer C
Pathophysiology of Haemostasis and Thrombosis, 30(6), 298-307 (2000)
Determination of phylloquinone (vitamin K1) in plasma and serum by HPLC with fluorescence detection
Wang LY, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 347(1-2), 199-207 (2004)
The content of phylloquinone (vitamin K1) in human milk, cows' milk and infant formula foods determined by high-performance liquid chromatography
Haroon Y, et al.
The Journal of Nutrition, 112(6), 1105-1117 (1982)

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