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M86685

Sigma-Aldrich

α-Methyltryptamine

99%

Synonym(s):

3-(2-Aminopropyl)indole

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About This Item

Empirical Formula (Hill Notation):
C11H14N2
CAS Number:
299-26-3
Molecular Weight:
174.24
EC Number:
206-073-7
MDL number:
MFCD00005654
UNSPSC Code:
12352116
PubChem Substance ID:
329818066

Quality Level

100

Assay

99%

form

solid

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

mp

98-100 °C (lit.)

SMILES string

CC(N)Cc1c[nH]c2ccccc12

InChI

1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3

InChI key

QSQQQURBVYWZKJ-UHFFFAOYSA-N

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300 + H310 + H330

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
11120AZ
09422AZ
01827MR
16214TN
09611PF

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Involvement of 5-hydroxytryptamine and dopamine neurones in the behavioural effects of alpha-methylytryptamine.
C A Marsden
Neuropharmacology, 19(8), 691-698 (1980-08-01)
I S Severina
Biochemistry international, 9(2), 219-228 (1984-08-01)
A new hitherto unknown important property of D-amphetamine (but not L-isomer) and DL-alpha-N-methyltryptamine was discovered. These substances decrease the irreversible inhibition by clorgyline of tyramine deamination without affecting a sharply expressed inhibitory effect of clorgyline on serotonin oxidation. As a
gamma-Aminobutyric acid (GABA) receptor stimulation. III. Effect of progabide (SL 76002) on norepinephrine, dopamine and 5-hydroxytryptamine turnover in rat brain areas.
B Scatton et al.
The Journal of pharmacology and experimental therapeutics, 220(3), 678-688 (1982-03-01)
C K Goldman et al.
European journal of pharmacology, 115(1), 11-19 (1985-09-10)
This study examines the feeding response induced by hypothalamic noradrenergic stimulation, in terms of the type and synaptic position of its mediating receptor. Tests with norepinephrine or the alpha 2 receptor agonist clonidine, injected into the area of the paraventricular
Diane M Boland et al.
Journal of analytical toxicology, 29(5), 394-397 (2005-08-18)
In February 2003, the Miami-Dade County Medical Examiner Department reported the first known death in the country related to alpha-methyltryptamine (AMT). AMT is an indole analogue of amphetamine investigated in the 1960s as an antidepressant, stimulant, and monoamine oxidase inhibitor.
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