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Sigma-Aldrich

6-Mercapto-1-hexanol

99%

Synonym(s):

6-Hydroxy-1-hexanethiol, 6-MCH, 6-Mercaptohexan-1-ol, 6-Mercaptohexanol, MCH

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About This Item

Linear Formula:
HS(CH2)6OH
CAS Number:
1633-78-9
Molecular Weight:
134.24
Beilstein:
1846871
MDL number:
MFCD00068552
UNSPSC Code:
12352300
PubChem Substance ID:
329764139
NACRES:
NA.23

Assay

99%

form

liquid

refractive index

n20/D 1.486 (lit.)

bp

225 °C (lit.)

density

0.981 g/mL at 25 °C (lit.)

SMILES string

SCCCCCCO

InChI

1S/C6H14OS/c7-5-3-1-2-4-6-8/h7-8H,1-6H2

InChI key

UGZAJZLUKVKCBM-UHFFFAOYSA-N

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Application

This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with alcohols can be further functionalized with various groups even when attached to gold nanoclusters.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

>230.0 °F - closed cup

Flash Point(C)

> 110 °C - closed cup

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Hua Tan et al.
The journal of physical chemistry. B, 110(43), 21690-21693 (2006-10-27)
Au-MCH nanoclusters of (1.5 +/- 0.3) nm diameter (MCH = 6-mercapto-1-hexanol, HS-(CH2)6-OH) have been prepared and characterized by Transmission Electron Microscopy (TEM), UV-visible, Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared (FTIR) absorption spectroscopies, X-ray Powder Diffraction (XRD), and Thermogravimetric Analysis
Andres Lombana et al.
Journal of peptide science : an official publication of the European Peptide Society, 20(7), 563-569 (2014-06-13)
Development of resistant bacteria onto biomaterials is a major problem leading to nosocomial infections. Antimicrobial peptides are good candidates for the generation of antimicrobial surfaces because of their broad-spectrum activity and their original mechanism of action (i.e. rapid lysis of
Wei Wen et al.
Biosensors & bioelectronics, 71, 13-17 (2015-04-17)
In this work, a sensitive exonuclease-assisted amplification electrochemical aptasensor through insertion approach was developed for the detection of mucin 1 (MUC 1). In order to construct the aptasensor, 6-Mercapto-1-hexanol (MCH) was used to block partial sites of gold electrode (GE)
Chapman, R. G.; et al.
Journal of the American Chemical Society, 122, 8303-8303 (2000)
Riccardo Funari et al.
Biosensors & bioelectronics, 169, 112578-112578 (2020-09-11)
The ongoing global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to active research in its associated diagnostics and medical treatments. While quantitative reverse transcription polymerase chain reaction (qRT-PCR) is the most reliable method to detect viral
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