677418

Hydroxyapatite

nanopowder, <200 nm particle size (BET), ≥97%, synthetic

• Synonym(s): Calcium phosphate tribasic, Calcium hydroxyphosphate, HAp, Hydroxylapatite, Tribasic calcium phosphate
• Linear Formula: [Ca₅(OH)(PO₄)₃]_x
• CAS Number: 12167-74-7
• Molecular Weight: 502.31
• EC Number: 235-330-6
• MDL number: MFCD00010904
• UNSPSC Code: 12352302
• PubChem Substance ID: 24885371
• NACRES: NA.23

Properties

• Assay: ≥97%
• form: nanopowder; solid
• surface area: >9.4 m²/g
• particle size: <200 nm (BET)
• mp: 1100 °C (lit.)
• SMILES string: [Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O
• InChI: 1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10
• InChI key: XYJRXVWERLGGKC-UHFFFAOYSA-D

Description

General description

Hydroxyapatite(HA) belongs to the family of Ca apatite which resembles natural bone in both structure and chemical composition. It can be prepared by various techniques such as chemical precipitation, hydrothermal, electrospinning, and self-propagating combustion. It is widely used as an implant material for bone regeneration, a drug carrier, and a gene delivery system due to its bioactive and biocompatible nature.

Application

Nanoscale hydroxyapatite particles can be used to prepare bone tissue engineering materials due to their slow biodegradability in situ, good osteoconductive and osteoinductive capabilities.

Poly (sodium 4-styrene sulfonate)-modified hydroxyapatite nanoparticles can be used as a drug carrier for vancomycin. Hydroxyapatite nanoparticles control the release of antibiotics after the implantation of a scaffold in the body.

Porous hydroxyapatite microspheres exhibit a high adsorptive capacity for heavy metals and can be used for the treatment of heavy metal contaminated water.

Features and Benefits

• Bioactive and biocompatible
• Good mechanical strength
• Porous structure
• Osteoconductive and osteointegrative properties

Legal Information

Product of Engi-Mat Co.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves