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268542

Sigma-Aldrich

Hydroxypropyl methacrylate

Mixture of hydroxypropyl and hydroxyisopropyl methacrylates, 97%, contains 180-220 ppm monomethyl ether hydroquinone as inhibitor

Synonym(s):

HPMA

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About This Item

CAS Number:
Beilstein:
1752228
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

vapor density

>1 (vs air)

vapor pressure

0.05 mmHg ( 20 °C)

Assay

97%

form

liquid

contains

180-220 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.447 (lit.)

bp

57 °C/0.5 mmHg (lit.)

density

1.066 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(=C)C(=O)OCCCO

InChI

1S/C7H12O3/c1-5(2)7(9)10-6(3)4-8/h6,8H,1,4H2,2-3H3

InChI key

ZMARGGQEAJXRFP-UHFFFAOYSA-N

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Application


  • Synthesis of poly hydroxypropyl methacrylate cryogel incorporated with Zn/Ce substituted hydroxyapatite nanoparticles for rejuvenation of femoral fracture: This study explores the synthesis of a cryogel incorporating hydroxypropyl methacrylate and Zn/Ce substituted hydroxyapatite nanoparticles, aimed at bone fracture healing (H Zhou, H Jiao, J Xu, Y Liu, S Wei, 2019).

  • Poly(Hydroxypropyl methacrylate-co-glycidyl methacrylate): Facile synthesis of well-defined hydrophobic gels containing hydroxy-functional methacrylates: This article presents the synthesis of hydrophobic gels using hydroxypropyl methacrylate and glycidyl methacrylate, useful in various material applications (N Orakdogen, B Sanay, 2017).

  • Initiated chemical vapor deposition of poly(Hydroxypropyl methacrylate) thin films: The study covers the chemical vapor deposition process for creating thin films of poly(hydroxypropyl methacrylate) on membranes, enhancing their functional properties (E Sevgili, M Karaman, 2019).

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

203.0 °F - closed cup

Flash Point(C)

95 °C - closed cup


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Tao Liu et al.
Biomaterials, 33(8), 2521-2531 (2011-12-30)
We report on a novel type of multifunctional pH-disintegrable micellar nanoparticles fabricated from asymmetrically functionalized β-cyclodextrin (β-CD) based star copolymers covalently conjugated with doxorubicin (DOX), folic acid (FA), and DOTA-Gd moieties for integrated cancer cell-targeted drug delivery and magnetic resonance
Tomáš Etrych et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 42(5), 527-539 (2011-03-12)
New biodegradable star polymer-doxorubicin (Dox) conjugates designed for passive tumor targeting were investigated and the present study described their synthesis, physico-chemical characterization, drug release and biodegradation. In the conjugates the core formed by poly(amido amine) (PAMAM) dendrimers was grafted with
M Talelli et al.
Bioconjugate chemistry, 22(12), 2519-2530 (2011-10-25)
Doxorubicin is an anthracycline anticancer agent that is commonly used in the treatment of a variety of cancers, but its application is associated with severe side effects. Biodegradable and thermosensitive polymeric micelles based on poly(ethylene glycol)-b-poly[N-(2-hydroxypropyl) methacrylamide-lactate] (mPEG-b-p(HPMAmLac(n))) have been
Araceli Espinosa-Jeffrey et al.
Advances in experimental medicine and biology, 760, 25-52 (2013-01-03)
Injury to the spinal cord disrupts ascending and descending axonal pathways and causes tissue damage with a subsequent limited cellular regeneration. Successful treatment would encompass the restoration of the cytoarchitecture, homeostasis and function all in dear need. Transplantation-based treatments using
Mareli Allmeroth et al.
Biomacromolecules, 12(7), 2841-2849 (2011-06-23)
There is a recognized need to create well-defined polymer probes for in vivo and clinical positron emission tomography (PET) imaging to guide the development of new generation polymer therapeutics. Using the RAFT polymerization technique in combination with the reactive ester

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