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260843

Sigma-Aldrich

2,3,4-Trihydroxybenzaldehyde

98%

Synonym(s):

Pyrogallol-4-carboxaldehyde

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About This Item

Linear Formula:
(HO)3C6H2CHO
CAS Number:
Molecular Weight:
154.12
Beilstein:
2328658
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

powder

mp

159-161 °C (lit.)

SMILES string

[H]C(=O)c1ccc(O)c(O)c1O

InChI

1S/C7H6O4/c8-3-4-1-2-5(9)7(11)6(4)10/h1-3,9-11H

InChI key

CRPNQSVBEWWHIJ-UHFFFAOYSA-N

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General description

Antimicrobial activity of carbohydrazone derived from 2,3,4-trihydroxybenzaldehyde against bacteria and fungi has been investigated. 2,3,4-trihydroxybenzaldehyde forms Schiff bases via [1+1] condensation with anthranilic acid.

Application

2,3,4-Trihydroxybenzaldehyde has been used in the preparation of 1,5-dimethyl-2-phenyl-4-[(1E)-(2,3,4-trihydroxybenzylidene)amino]-1H-pyrazol-3(2H)-one.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Yuan Chen et al.
International journal of biological macromolecules, 143, 714-723 (2019-11-15)
In this study, the structure of inulin was chemically modified by Schiff bases in order to improve its biological activity. A total of 6 kinds of inulin derivatives were synthesized according to aza-Wittig reaction. Their structures were confirmed by FTIR
Eila Pelttari et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 62(7-8), 483-486 (2007-10-05)
Certain substituted salicylaldehydes are known to have highly potent antimicrobial activity against bacteria and fungi, but the mechanism underlying this remarkable activity is not known, and almost nothing has been reported on the effects of further modification of the structures
B D Vázquez-Cabral et al.
Chemico-biological interactions, 272, 1-9 (2017-05-10)
Black tea infusion is the common substrate for preparing kombucha; however other sources such as oak leaves infusions can be used for the same purpose. Almost any white oak species have been used for medicinal applications by some ethnic groups
Sari Honda et al.
Free radical biology & medicine, 106, 228-235 (2017-02-23)
In this study, the mechanism of the xanthine oxidase (XO) inhibitory activity of pyrogallol, the main inhibitor found in roasted coffee, was investigated. Pyrogallol was unstable and readily converted to purpurogallin in a pH 7.4 solution, a physiological model of
1, 5-Dimethyl-2-phenyl-4-[(1E)-(2, 3, 4-trihydroxybenzylidene) amino]-1H-pyrazol-3 (2H)-one.
Sun Y-F, et al.
Acta Crystallographica Section E, Structure Reports Online, 63(5), o2522-o2523 (2007)

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