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162663

Sigma-Aldrich

DL-2-Aminobutyric acid

99%, for peptide synthesis, ReagentPlus®

Synonym(s):

AABA, Homoalanine, alpha-amino-n-butyric acid

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About This Item

Linear Formula:
C2H5CH(NH2)CO2H
CAS Number:
2835-81-6
Molecular Weight:
103.12
Beilstein:
635889
EC Number:
220-616-5
MDL number:
MFCD00008093
UNSPSC Code:
12352116
PubChem Substance ID:
24849999
NACRES:
NA.22

product name

DL-2-Aminobutyric acid, ReagentPlus®, 99%

product line

ReagentPlus®

Assay

99%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

291 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CCC(N)C(O)=O

InChI

1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)

InChI key

QWCKQJZIFLGMSD-UHFFFAOYSA-N

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General description

DL-2-Aminobutyric acid also known as α-aminobutyric acid, is commonly used in solution-phase peptide synthesis.

Application

DL-2-Aminobutyric acid can be used to synthesize 2-(2,5-dioxopyrrolidin-1-yl) butanoic acid.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The iron(II)- and 2-(oxo)glutarate-dependent (Fe/2OG) oxygenases catalyze an array of challenging transformations, but how individual members of the enzyme family direct different outcomes is poorly understood. The Fe/2OG halogenase, SyrB2, chlorinates C4 of its native substrate, l-threonine appended to the
Fatemeh Mahmoodani et al.
Journal of food science and technology, 51(9), 1847-1856 (2014-09-06)
Skin and bone gelatins of pangasius catfish (Pangasius sutchi) were hydrolyzed with alcalase to isolate Angiotensin Converting Enzyme (ACE) inhibitory peptides. Samples with the highest degree of hydrolysis (DH) were separated into different fractions with molecular weight cut-off (MWCO) sizes
Christian Rausch et al.
Proteins, 81(5), 774-787 (2012-12-15)
Apart from their crucial role in metabolism, pyridoxal 5'-phosphate (PLP)-dependent aminotransferases (ATs) constitute a class of enzymes with increasing application in industrial biotechnology. To provide better insight into the structure-function relationships of ATs with biotechnological potential we performed a fundamental
Kun Huang et al.
The Journal of biological chemistry, 282(48), 35337-35349 (2007-09-22)
The contribution of the insulin A-chain to receptor binding is investigated by photo-cross-linking and nonstandard mutagenesis. Studies focus on the role of Val(A3), which projects within a crevice between the A- and B-chains. Engineered receptor alpha-subunits containing specific protease sites
Young-Man Seo et al.
Organic & biomolecular chemistry, 10(12), 2482-2485 (2012-02-22)
A deracemization method was developed to generate optically pure L-homoalanine from racemic homoalanine using D-amino acid oxidase and ω-transaminase. A whole cell reaction using a biphasic system converted 500 mM racemic homoalanine to 485 mM L-homoalanine (>99% ee).
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