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SML3147

Sigma-Aldrich

GSK046

≥98% (HPLC)

Synonym(s):

iBET-BD2, 4-acetamido-3-fluoro-N-(trans-4-hydroxycyclohexyl)-5-[(1S)-1-phenylethoxy]benzamide; 4-Acetamido-3-fluoro-N-((1R,4S)-4-hydroxycyclohexyl)-5-((S)-1-phenylethoxy)benzamide

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About This Item

Empirical Formula (Hill Notation):
C23H27FN2O4
CAS Number:
2474876-09-8
Molecular Weight:
414.47
MDL number:
MFCD32858297
UNSPSC Code:
12352107
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

storage temp.

2-8°C

SMILES string

O=C(N[C@H]1CC[C@H](O)CC1)C2=CC(F)=C(NC(C)=O)C(O[C@H](C3=CC=CC=C3)C)=C2

General description

GSK046 is an orally bioavailable small molecule. Its structure contains a poly-substituted phenyl ring in the center. GSK046 reduces immuno-inflammation by inhibiting the production of monocyte chemoattractant protein 1 (MCP-1), a chemokine involved in the regulation of macrophage activation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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