SBPV04

BCRP Human Vesicular Transport Kit

membrane based kit for Human BCRP Vesicular Transport Assays

• Synonym(s): ABCG2, Breast Cancer Resistance Protein
• UNSPSC Code: 12352200

Properties

• recombinant: expressed in human cells
• UniProt accession no.: Q9UNQ0
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... ABCG2(9429)

Description

General description

SOLVO Biotechnology offers ready-to-use assay kits for efflux and uptake transporters. SOLVO′s PREDIVEZ Vesicular Transport Assay Kits are suitable for efflux transporter inhibition studies. The kits are designed to test the inhibitory effect of one or more test compounds on the vesicular transport of a probe substrate. In most cases a fluorescent probe substrate is included. Kits contain all reagents and solutions necessary to conduct the drug-transporter interaction assay of need.

Application

The PREDIVEZTM Vesicular Transport Kit is a simple and powerful tool to investigate drug transporter interactions. It provides information on any interaction between the ABC transporter and the drug candidate that would affect the transport of the fluorescent or radiolabeled or cold.

PREDIVEZTM vesicular transport kits are available in three sizes 3, 6 or 9 compound sizes. The kits contain the sufficient amount of reagents and membrane preparations needed for the testing of 3 compounds per 96-well plate. Each kit is accompanied by a CD that includes the assay protocol, an Excel spreadsheet with a data processing template, SDS and the inhibition curves with reference compounds.

Physical form

Supplied as frozen membrane vesicles, containing 5 mg/ml membrane protein, labeled with volume, catalog number (transporter), date of production, protocols and necessary reagents sufficent for the analysis of 3, 6, or 9 test compounds

Legal Information

Distributed for SOLVO Biotechnology, Inc.