RAB0908
Rat Mag / Myelin-associated Glycoprotein ELISA Kit
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
species reactivity
rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 10 pg/mL
standard curve range: 10.24-2500 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Mag(29409)
General description
The antibody pair provided in this kit recognizes rat MAG / Myelin-associated Glycoprotein / Siglec-4a.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Myelin-associated glycoprotein (MAG) is expressed in Schwann cells and oligodendrocytes. It inhibits the growth of axons. MAG also has a role in signal transduction pathways and cell adhesion. In complex with the neurite outgrowth inhibitor (Nogo) receptor, MAG acts on neurons via the p75 receptor. It activates and modulates the function of Ras homolog gene family, member A (RhoA).
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Myelin-associated glycoprotein inhibits the neuronal differentiation of neural progenitors.
Li X, et al.
Neuroreport, 20(7), 708-712 (2009)
Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody.
Thompson HJ, et al.
The European Journal of Neuroscience, 24(11), 3063-3072 (2006)
Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism.
Mimura F, et al.
The Journal of Biological Chemistry, 281(23), 15970-15979 (2006)
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