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M1765

Sigma-Aldrich

1-Lauroyl-rac-glycerol

≥99%

Synonym(s):

1-Monododecanoyl-rac-glycerol, 1-Monolaurin, 1-Monolauroyl-rac-glycerol, rac-Glycerol 1-laurate, DL-α-Laurin

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About This Item

Linear Formula:
H3C(CH2)10COOCH2CH(OH)CH2OH
CAS Number:
142-18-7
Molecular Weight:
274.40
Beilstein:
1726740
EC Number:
205-526-6
MDL number:
MFCD00037815
UNSPSC Code:
12352211
PubChem Substance ID:
24896686
NACRES:
NA.25

biological source

plant

Quality Level

200

Assay

≥99%

form

powder

functional group

ketone

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCC(=O)OCC(O)CO

InChI

1S/C15H30O4/c1-2-3-4-5-6-7-8-9-10-11-15(18)19-13-14(17)12-16/h14,16-17H,2-13H2,1H3

InChI key

ARIWANIATODDMH-UHFFFAOYSA-N

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Biochem/physiol Actions

Monolaurin (1-Lauroyl-rac-glycerol) is used as an antimicrobial agent in various formulas and microemulsions and as a methane mitigation agent in ruminants.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Patrick M Schlievert et al.
Antimicrobial agents and chemotherapy, 52(12), 4448-4454 (2008-10-08)
Glycerol monolaurate (GML) is a fatty acid monoester that inhibits growth and exotoxin production of vaginal pathogens and cytokine production by vaginal epithelial cells. Because of these activities, and because of the importance of cytokine-mediated immune activation in human immunodeficiency
Stewart Bachan et al.
Bioorganic & medicinal chemistry, 19(16), 4803-4811 (2011-07-26)
Inspired by the anti-human immunodeficiency virus (HIV) activity of analogues of β-galactosylceramide (GalCer), a set of mono- and di-saccharide fatty acid esters were designed as GalCer mimetics and their binding to the V3 loop peptide of HIV-1 and anti-HIV activity
Fenja Klevenhusen et al.
Anaerobe, 17(5), 232-238 (2011-07-27)
Before being able to implement effective ruminal methane mitigation strategies via feed supplementation, the assessment of side effects on ruminal fermentation and rumen microbial populations is indispensable. In this respect we investigated the effects of monolaurin, a methane-mitigating lipid, on
Fenja Klevenhusen et al.
The British journal of nutrition, 102(9), 1308-1317 (2009-06-10)
Mitigation of methanogenesis in ruminants has been an important goal for several decades. Free lauric acid, known to suppress ruminal methanogenesis, has a low palatability; therefore, in the present study the aim was to evaluate the mitigation efficacy of its
Ketan Patel et al.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 21(1), 27-27 (2013-03-28)
Lumefantrine, an antimalarial molecule has very low and variable bioavailability owing to its extremely poor solubility in water. It is recommended to be taken with milk to enhance its solubility and bioavailability. The aim of present study was to develop
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