L5011

Leukotriene D₄

~50 μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6), ≥97%

• Synonym(s): LTD₄
• Empirical Formula (Hill Notation): C₂₅H₄₀N₂O₆S
• CAS Number: 73836-78-9
• Molecular Weight: 496.66
• MDL number: MFCD00036839
• UNSPSC Code: 51111800
• PubChem Substance ID: 24896383
• NACRES: NA.77

Properties

• Quality Level: 200
• Assay: ≥97%
• concentration: ~50 μg/mL (in methanol/ammonium acetate buffer, 70:30, pH 5.6)
• shipped in: dry ice
• storage temp.: −70°C
• SMILES string: CCCCC\C=C\C/C=C\C=C\C=C\[C@@H](SC[C@@H](N)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O
• InChI: 1S/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6+,10-9-,12-11+,16-13+/t20-,21+,22-/m1/s1
• InChI key: YEESKJGWJFYOOK-GKWRKXFUSA-N

Description

Biochem/physiol Actions

Slow reacting substance of anaphylaxis (SRS-A). Potent bronchoconstrictor and mediator of asthmatic and inflammatory processes. Increases cytosolic free Ca²⁺ in epithelial cells.

Features and Benefits

This compound is featured on the Leukotriene Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Packaged under argon.

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 49.5 °F
• Flash Point(C): 9.7 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves