C6445

Sodium cholate hydrate

BioXtra, ≥99%

• Synonym(s): 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt
• Empirical Formula (Hill Notation): C₂₄H₃₉NaO₅ · xH₂O
• CAS Number: 206986-87-0
• Molecular Weight: 430.55 (anhydrous basis)
• Beilstein: 3582354
• EC Number: 206-643-5
• MDL number: MFCD00150749
• UNSPSC Code: 12161900
• PubChem Substance ID: 24892867
• NACRES: NA.25

Properties

• description: anionic
• product line: BioXtra
• Assay: ≥99%
• form: powder
• mol wt: micellar avg mol wt 900-1300
• aggregation number: 2-3
• impurities: ≤0.05% Phosphorus (P); ≤0.1% Insoluble matter
• CMC: 9-15 mM (20-25°C)
• solubility: H₂O: 1 M, clear, faintly yellow to yellow
• anion traces: sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.005%; Ca: ≤0.005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.0005%
• HLB: 18
• SMILES string: O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
• InChI key: MUVVIYFKOVLQHL-RCVKHMDESA-M

Description

General description

Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins.

Application

Sodium cholate hydrate has been used in a study to assess infiltration of pressurized promoter solutions in a mesoporous silica.

Sodium cholate hydrate has been used:

• as a component of biofilm growth media along with tryptic soy broth (TSB) to test the effects of each bile salt on biofilm formation
• as a detergent to study its effect on cannabinoid receptor 1 (CB1) detection by western blot
• as a promoter to prepare solution B for the synthesis of tungsten disulfide (WS₂) on a SiO₂/Si wafer

Features and Benefits

• pH range 5-8
• Suitable for membrane technology and culture media

Safety Information

• Hazard Statements: H412
• Precautionary Statements: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves